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4E-Binding Protein Phosphorylation and Eukaryotic Initiation Factor-4E Release Are Required for Airway Smooth Muscle Hypertrophy
The molecular mechanisms of airway smooth muscle hypertrophy, a feature of severe asthma, are poorly understood. We previously established a conditionally immortalized human bronchial smooth muscle cell line with a temperature-sensitive SV40 large T antigen. Temperature shift and loss of large T cau...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1578595/ https://ncbi.nlm.nih.gov/pubmed/15901615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2004-0411OC |
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