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The Transition between the B and Z Conformations of DNA Investigated by Targeted Molecular Dynamics Simulations with Explicit Solvation

The transition between the B and Z conformations of double-helical deoxyribonucleic acid (DNA) belongs to the most complex and elusive conformational changes occurring in biomolecules. Since the accidental discovery of the left-handed Z-DNA form in the late 1970s, research on this DNA morphology has...

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Autori principali: Kastenholz, Mika A., Schwartz, Thomas U., Hünenberger, Philippe H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578494/
https://ncbi.nlm.nih.gov/pubmed/16998239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.083667
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