Abnormalities of in vitro immunoglobulin production in apparently healthy haemophiliacs: relationship with alterations of T cell subsets and with HTLV-III seropositivity.

The pokeweed mitogen (PWM)-induced immunoglobulin (Ig) production by cultures of peripheral blood mononuclear cells (PBMC) was reduced in healthy haemophiliacs treated with commercial factor VIII (or IX) concentrate, whereas the spontaneous IgG synthesis in vitro was enhanced. PWM-induced Ig product...

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Hauptverfasser: Biagiotti, R, Giudizi, M G, Almerigogna, F, Mazzetti, M, Alessi, A, Del Prete, G F, Rafanelli, D, Fiorilli, M, Morfini, M, Romagnani, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1577369/
https://ncbi.nlm.nih.gov/pubmed/3009063
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