Direct induction of human B-cell differentiation by recombinant interleukin-2.

Recombinant interleukin-2 (rIL-2) induced highly purified human tonsillar B cells to differentiate into immunoglobulin (Ig)-producing cells in vitro. The B-cell response was not due to rIL-2-contaminating substances, but reflected the activity of IL-2 itself, since it was inhibited by addition to th...

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Autores principales: Romagnani, S, Del Prete, G, Giudizi, M G, Biagiotti, R, Almerigogna, F, Tiri, A, Alessi, A, Mazzetti, M, Ricci, M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1452648/
https://ncbi.nlm.nih.gov/pubmed/3486819
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