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The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts

We investigated the contribution of the xeroderma pigmentosum group C (XPC) gene to DNA repair. We stably transfected XPC cells (XP4PA-SV-EB) with XPC cDNA and selected a partially corrected (XP4PA-SE1) and a fully corrected (XP4PA-SE2) clone. Cell survival after UVC (254 nm) exposure was low for XP...

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Detalles Bibliográficos
Main Authors: Emmert, Steffen, Kobayashi, Nobuhiko, Khan, Sikandar G., Kraemer, Kenneth H.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC15769/
https://ncbi.nlm.nih.gov/pubmed/10681431
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