The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts

We investigated the contribution of the xeroderma pigmentosum group C (XPC) gene to DNA repair. We stably transfected XPC cells (XP4PA-SV-EB) with XPC cDNA and selected a partially corrected (XP4PA-SE1) and a fully corrected (XP4PA-SE2) clone. Cell survival after UVC (254 nm) exposure was low for XP...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Emmert, Steffen, Kobayashi, Nobuhiko, Khan, Sikandar G., Kraemer, Kenneth H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2000
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15769/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040559697
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