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Some structural determinants of the antiproliferative effect of heparin-like molecules on human airway smooth muscle

1. Accumulation of airway smooth muscle (ASM) and its infiltration by mast cells are key pathological features of airway remodelling in asthma. Heparin, a major component of mast cell granules, inhibits ASM proliferation by an unknown mechanism. Here, unfractionated heparins and related glycosaminog...

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Detalhes bibliográficos
Main Authors: Kanabar, Varsha, Hirst, Stuart J, O'Connor, Brian J, Page, Clive P
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576283/
https://ncbi.nlm.nih.gov/pubmed/16025136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706333
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