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Structural features of phenol derivatives determining potency for activation of chloride currents via α(1) homomeric and α(1)β heteromeric glycine receptors

1. Phenol derivatives constitute a family of neuroactive compounds. The aim of our study was to identify structural features that determine their modulatory effects at glycine receptors. 2. We investigated the effects of four methylated phenol derivatives and two halogenated analogues on chloride in...

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Main Authors: Haeseler, Gertrud, Ahrens, Jörg, Krampfl, Klaus, Bufler, Johannes, Dengler, Reinhard, Hecker, Hartmut, Aronson, Jeffrey K, Leuwer, Martin
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576211/
https://ncbi.nlm.nih.gov/pubmed/15912136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706254
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