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The antidepressant imipramine inhibits M current by activating a phosphatidylinositol 4,5-bisphosphate (PIP(2))-dependent pathway in rat sympathetic neurones
1. Little is known about the intracellular actions of imipramine (IMI) in the regulation of ion channels. We tested the action of IMI on the intracellular cascade that regulates M current (I(M)) in superior cervical ganglion neurones (SCGs). 2. Dialysis of the cells with GDPβS, a G protein signaling...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576193/ https://ncbi.nlm.nih.gov/pubmed/15852030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706239 |
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