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Pharmacodynamics of propiverine and three of its main metabolites on detrusor contraction

1. Besides its antimuscarinic effects, propiverine may possess an additional mode of action. We compared the effects of propiverine, three of its metabolites (M-5, M-6, M-14) and atropine in human, pig and mouse urinary bladder preparations in order to elucidate the nature of a possible additional m...

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Bibliografiske detaljer
Main Authors: Wuest, Melinda, Hecht, Juliane, Christ, Torsten, Braeter, Manfred, Schoeberl, Christian, Hakenberg, Oliver W, Wirth, Manfred P, Ravens, Ursula
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576185/
https://ncbi.nlm.nih.gov/pubmed/15880140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706244
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