Activation of cannabinoid CB(2) receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling

1. Cannabinoid (CB) receptor agonists have potential utility as anti-inflammatory drugs for the treatment of many disease conditions. In the present study, we investigated the effects of the synthetic CB(2) ligand, JWH-133 on the production of interleukins (ILs), IL-12 and IL-10 by lipopolyssacharid...

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Hlavní autoři: Correa, Fernando, Mestre, Leyre, Docagne, Fabian, Guaza, Carmen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576166/
https://ncbi.nlm.nih.gov/pubmed/15821753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706215
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