Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1 )receptors

BACKGROUND: VCAM-1 represents one of the most important adhesion molecule involved in the transmigration of blood leukocytes across the blood-brain barrier (BBB) that is an essential step in the pathogenesis of MS. Several evidences have suggested the potential therapeutic value of cannabinoids (CBs...

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Main Authors: Mestre, Leyre, Iñigo, Paula M, Mecha, Miriam, Correa, Fernando G, Hernangómez-Herrero, Miriam, Loría, Frida, Docagne, Fabian, Borrell, José, Guaza, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173342/
https://ncbi.nlm.nih.gov/pubmed/21851608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-102
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