Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways

1. Artocarpol A (ART), a natural phenolic compound isolated from Artocarpus rigida, stimulated a slow onset and long-lasting superoxide anion generation in rat neutrophils, whereas only slightly activated the NADPH oxidase in a cell-free system. 2. Pretreatment of neutrophils with pertussis toxin (1...

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Main Authors: Kuan, Yu-Hsiang, Lin, Ruey-Hseng, Tsao, Lo-Ti, Lin, Chun-Nan, Wang, Jih-Pyang
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576157/
https://ncbi.nlm.nih.gov/pubmed/15806113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706205
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