Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [(3)H]2-furoyl-LIGRL-NH(2), to human PAR2

1. To determine the binding characteristics of a highly potent agonist for protease-activated receptor-2 (PAR2), 2-furoyl-Leu-Ile-Gly-Arg-Leu-amide (2-furoyl-LIGRL-NH(2)), whole-cell binding assays were performed utilising a radioactive ligand, [(3)H]2-furoyl-LIGRL-NH(2). 2. Specific binding of [(3)...

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Auteurs principaux: Kanke, Toru, Ishiwata, Hiroyuki, Kabeya, Mototsugu, Saka, Masako, Doi, Takeshi, Hattori, Yukio, Kawabata, Atsufumi, Plevin, Robin
Format: Artigo
Langue:Inglês
Publié: 2005
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Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576136/
https://ncbi.nlm.nih.gov/pubmed/15765104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706189
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