A selective novel low-molecular-weight inhibitor of IκB kinase-β (IKK-β) prevents pulmonary inflammation and shows broad anti-inflammatory activity

1. Pulmonary inflammatory diseases such as asthma are characterized by chronic, cell-mediated inflammation of the bronchial mucosa. 2. Recruitment and activation of inflammatory cells is orchestrated by a variety of mediators such as cytokines, chemokines, or adhesion molecules, the expression of wh...

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Detalhes bibliográficos
Main Authors: Ziegelbauer, Karl, Gantner, Florian, Lukacs, Nicholas W, Berlin, Aaron, Fuchikami, Kinji, Niki, Toshiro, Sakai, Katsuya, Inbe, Hisayo, Takeshita, Keisuke, Ishimori, Mina, Komura, Hiroshi, Murata, Toshiki, Lowinger, Timothy, Bacon, Kevin B
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576128/
https://ncbi.nlm.nih.gov/pubmed/15753951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706176
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