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Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome
Drug induced long QT syndrome (LQTS) can lead to cardiac arrhythmias and sudden death, and has emerged as a worldwide problem. Most drugs that cause this are thought to directly block a specific cardiac ion channel (KCNH2 or hERG) that carries the rapidly activating delayed rectifier potassium curre...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576114/ https://ncbi.nlm.nih.gov/pubmed/15711590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706143 |
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