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Synergistic and additive interactions of the cannabinoid agonist CP55,940 with μ opioid receptor and α(2)-adrenoceptor agonists in acute pain models in mice
1. Cannabinoid receptor agonists elicit analgesic effects in acute and chronic pain states via spinal and supraspinal pathways. We investigated whether the combination of a cannabinoid agonist with other classes of antinociceptive drugs exerted supra-additive (synergistic) or additive effects in acu...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576059/ https://ncbi.nlm.nih.gov/pubmed/15778704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706045 |
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