Synergistic and additive interactions of the cannabinoid agonist CP55,940 with μ opioid receptor and α(2)-adrenoceptor agonists in acute pain models in mice

1. Cannabinoid receptor agonists elicit analgesic effects in acute and chronic pain states via spinal and supraspinal pathways. We investigated whether the combination of a cannabinoid agonist with other classes of antinociceptive drugs exerted supra-additive (synergistic) or additive effects in acu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tham, Shao M, Angus, James A, Tudor, Elizabeth M, Wright, Christine E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576059/
https://ncbi.nlm.nih.gov/pubmed/15778704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706045
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