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Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

1. We have characterised the effects of piperine, a pungent alkaloid found in black pepper, on the human vanilloid receptor TRPV1 using whole-cell patch-clamp electrophysiology. 2. Piperine produced a clear agonist activity at the human TRPV1 receptor yielding rapidly activating whole-cell currents...

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Bibliografische gegevens
Hoofdauteurs: McNamara, Fergal N, Randall, Andrew, Gunthorpe, Martin J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576058/
https://ncbi.nlm.nih.gov/pubmed/15685214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706040
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