Addition of a signal peptide sequence to the α(1D)-adrenoceptor gene increases the density of receptors, as determined by [(3)H]-prazosin binding in the membranes

1. Both in mammalian tissues and in transfected cells, only low levels of α(1D)-adrenoceptors are detected in radioligand binding studies. It has been implicated that the comparatively long N-terminal tail of the α(1D)-adrenoceptor is responsible for the inefficient surface expression of the recepto...

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Bibliografiske detaljer
Main Authors:	Petrovska, Ramona, Kapa, Ivo, Klovins, Janis, Schiöth, Helgi B, Uhlén, Staffan
Format:	Artigo
Sprog:	Inglês
Udgivet:	2005
Fag:	Papers
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1576044/ https://ncbi.nlm.nih.gov/pubmed/15678090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706087
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Addition of a signal peptide sequence to the α(1D)-adrenoceptor gene increases the density of receptors, as determined by [(3)H]-prazosin binding in the membranes

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