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Addition of a signal peptide sequence to the α(1D)-adrenoceptor gene increases the density of receptors, as determined by [(3)H]-prazosin binding in the membranes
1. Both in mammalian tissues and in transfected cells, only low levels of α(1D)-adrenoceptors are detected in radioligand binding studies. It has been implicated that the comparatively long N-terminal tail of the α(1D)-adrenoceptor is responsible for the inefficient surface expression of the recepto...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576044/ https://ncbi.nlm.nih.gov/pubmed/15678090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706087 |
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