Anxiogenic properties of an inverse agonist selective for α3 subunit-containing GABA(A) receptors

1. α3IA (6-(4-pyridyl)-5-(4-methoxyphenyl)-3-carbomethoxy-1-methyl-1H-pyridin-2-one) is a pyridone with higher binding and functional affinity and greater inverse agonist efficacy for GABA(A) receptors containing an α3 rather than an α1, α2 or α5 subunit. If doses are selected that minimise the occu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Atack, John R, Hutson, Peter H, Collinson, Neil, Marshall, George, Bentley, Graham, Moyes, Christopher, Cook, Susan M, Collins, Ian, Wafford, Keith, McKernan, Ruth M, Dawson, Gerard R
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576012/
https://ncbi.nlm.nih.gov/pubmed/15655523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados