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Effect of the statin atorvastatin on intracellular signalling by the prostacyclin receptor in vitro and in vivo

1. Prostacyclin plays a central role within the vasculature. We have previously established that the prostacyclin receptor (IP) undergoes isoprenylation, a lipid modification obligate for its function. The aim of the current study was to investigate the effect of the hydroxy methyl glutaryl co-enzym...

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Detalhes bibliográficos
Main Authors: O'Meara, Sarah J, Kinsella, B Therese
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575340/
https://ncbi.nlm.nih.gov/pubmed/15326037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705947
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