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Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk

1. The aim of this study was to analyse the effects of eliprodil, a noncardiac drug with neuroprotective properties, on the cardiac repolarisation under in vitro circumstances, under normal conditions and after the attenuation of the ‘repolarisation reserve' by blocking the inward rectifier pot...

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Detalhes bibliográficos
Main Authors: Lengyel, Csaba, Dézsi, László, Biliczki, Péter, Horváth, Csilla, Virág, László, Iost, Norbert, Németh, Miklós, Tálosi, László, Papp, Julius Gy, Varró, András
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575264/
https://ncbi.nlm.nih.gov/pubmed/15302678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705901
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