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Ranolazine: Ion-channel-blocking actions and in vivo electrophysiological effects
1. Ranolazine is a novel anti-ischemic drug that prolongs the QT interval. To evaluate the potential mechanisms and consequences, we studied: (i) Ranolazine's effects on HERG and IsK currents in Xenopus oocytes with two-electrode voltage clamp; (ii) effects of ranolazine, compared to D-sotalol,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1575187/ https://ncbi.nlm.nih.gov/pubmed/15277312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705879 |
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