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Inhibitory effects of digoxin and digitoxin on corticosterone production in rat zona fasciculata-reticularis cells

1. The aim of the present study was to investigate the direct effects and action mechanisms of digitalis on the production of corticosterone in rat adrenocortical cells. 2. Male rats were challenged with digoxin (1 μg ml(−1) kg(−1)) in the presence or absence of adrenocorticotropin (ACTH, 5 μg ml(−1...

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Autors principals: Wang, Shyi-Wu, Pu, Hsaio-Fung, Kan, Shu-Fen, Tseng, Chiung-I, Lo, Ming-Jae, Wang, Paulus S
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575169/
https://ncbi.nlm.nih.gov/pubmed/15249423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705777
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