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Inhibitory effects of digoxin and digitoxin on corticosterone production in rat zona fasciculata-reticularis cells

1. The aim of the present study was to investigate the direct effects and action mechanisms of digitalis on the production of corticosterone in rat adrenocortical cells. 2. Male rats were challenged with digoxin (1 μg ml(−1) kg(−1)) in the presence or absence of adrenocorticotropin (ACTH, 5 μg ml(−1...

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Bibliografiske detaljer
Main Authors: Wang, Shyi-Wu, Pu, Hsaio-Fung, Kan, Shu-Fen, Tseng, Chiung-I, Lo, Ming-Jae, Wang, Paulus S
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575169/
https://ncbi.nlm.nih.gov/pubmed/15249423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705777
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