Llwytho...

A novel inhibitor of vacuolar ATPase, FR167356, which can discriminate between osteoclast vacuolar ATPase and lysosomal vacuolar ATPase

1. Vacuolar ATPase (V-ATPase) has been proposed as a drug target in lytic bone diseases. Studies of bafilomycin derivatives suggest that the key issue regarding the therapeutic usefulness of V-ATPase inhibitors is selective inhibition of osteoclast V-ATPase. Previous efforts to develop therapeutic i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Niikura, Kazuaki, Takano, Mikiko, Sawada, Masae
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574973/
https://ncbi.nlm.nih.gov/pubmed/15148249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705812
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