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Inhibitors of the V(0) subunit of the vacuolar H(+)-ATPase prevent segregation of lysosomal- and secretory-pathway proteins
The vacuolar H(+)-ATPase (V-ATPase) establishes pH gradients along secretory and endocytic pathways. Progressive acidification is essential for proteolytic processing of prohormones and aggregation of soluble content proteins. The V-ATPase V(0) subunit is thought to have a separate role in budding a...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Company of Biologists
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746133/ https://ncbi.nlm.nih.gov/pubmed/19737820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.034298 |
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