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Enhanced inhibition of the EDHF phenomenon by a phenyl methoxyalaninyl phosphoramidate derivative of dideoxyadenosine

In rabbit arteries endogenous production of cAMP facilitates electrotonic signalling via gap junctions, thus explaining the ability of P-site inhibitors of adenylyl cyclase to attenuate EDHF-type responses. In the present study, we show that a lipophilic phosphoramidate pronucleotide derivative of d...

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Detalhes bibliográficos
Main Authors: Griffith, Tudor M, Chaytor, Andrew T, Edwards, David H, Daverio, Felice, McGuigan, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574937/
https://ncbi.nlm.nih.gov/pubmed/15131001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705782
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