Hydrogen sulfide (H(2)S) stimulates capsaicin-sensitive primary afferent neurons in the rat urinary bladder

1. In the rat isolated urinary bladder, NaHS (30 μM–3 mM) and capsaicin (10 nM–3 μM) produced concentration-dependent contractile responses (pEC(50)=3.5±0.02 and 7.1±0.02, respectively) undergoing dramatic tachyphylaxis. In preparations in which sensory nerves were rendered desensitized (defunctiona...

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Bibliographic Details
Main Authors: Patacchini, Riccardo, Santicioli, Paolo, Giuliani, Sandro, Maggi, Carlo Alberto
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Special Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574935/
https://ncbi.nlm.nih.gov/pubmed/15051627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705764
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