Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity

BACKGROUND: There is a large body of evidence which suggests that bile acids increase the risk of colon cancer and act as tumor promoters, however, the mechanism(s) of bile acids mediated tumorigenesis is not clear. Previously we showed that deoxycholic acid (DCA), a tumorogenic bile acid, and ursod...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Powell, Ashley A, Akare, Sandeep, Qi, Wenqing, Herzer, Pascal, Jean-Louis, Samira, Feldman, Rebecca A, Martinez, Jesse D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2006
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574338/
https://ncbi.nlm.nih.gov/pubmed/16948850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-219
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