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Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease

1. Methylenetetrahydrofolate reductase (MTHFR) is a regulating enzyme in folate-dependant homocysteine remethylation, because it catalyses the reduction of 5,10 methylenetetrahydrofolate to 5-methyltetrahydrofolate (5-MTHF). 2. Subjects homozygous for the 677C → T mutation in the MTHFR enzyme suffer...

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Detalhes bibliográficos
Main Authors: Willems, Frank F, Boers, Godfried H J, Blom, Henk J, Aengevaeren, Wim R M, Verheugt, Freek W A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574248/
https://ncbi.nlm.nih.gov/pubmed/14769778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705446
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