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Na(+)/H(+) exchange inhibition attenuates left ventricular remodeling and preserves systolic function in pressure-overloaded hearts

1. Cardiac hypertrophy is a homeostatic response to elevated afterload. Na(+)/H(+) exchanger (NHE) inhibition reduces the hypertrophic response in animal models of left ventricular hypertrophy (LVH) and myocardial infarction. We examined the effect of chronic treatment with cariporide, a selective i...

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Autors principals: Marano, Giuseppe, Vergari, Alessandro, Catalano, Liviana, Gaudi, Simona, Palazzesi, Sergio, Musumeci, Marco, Stati, Tonino, Ferrari, Alberto U
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574214/
https://ncbi.nlm.nih.gov/pubmed/14718258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705631
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