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Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster
1. The GABA-modulating and GABA-mimetic activities of the monoterpenoid thymol were explored on human GABA(A) and Drosophila melanogaster homomeric RDL(ac) GABA receptors expressed in Xenopus laevis oocytes, voltage-clamped at −60 mV. The site of action of thymol was also investigated. 2. Thymol, 1–...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574153/ https://ncbi.nlm.nih.gov/pubmed/14623762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705542 |
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