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The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway

1. Arvanil (N-arachidonoylvanillamine), a nonpungent capsaicin–anandamide hybrid molecule, has been shown to exert biological activities through VR1/CB1-dependent and -independent pathways. We have found that arvanil induces dose-dependent apoptosis in the lymphoid Jurkat T-cell line, but not in per...

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Detalhes bibliográficos
Main Authors: Sancho, Rocío, de la Vega, Laureano, Appendino, Giovanni, Di Marzo, Vincenzo, Macho, Antonio, Muñoz, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574119/
https://ncbi.nlm.nih.gov/pubmed/14530215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705532
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