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Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca(2+) sensitivity in the bovine middle cerebral artery
1. The role of Rho kinase in Ca(2+) sensitization of the contractile apparatus in smooth muscle was investigated in the bovine middle cerebral artery. 2. U46619, a thromboxane A(2) analog, induced a greater sustained contraction with a smaller [Ca(2+)](i) elevation than that seen with 118 mM K(+). T...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574090/ https://ncbi.nlm.nih.gov/pubmed/14530221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705487 |
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