Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca(2+) sensitivity in the bovine middle cerebral artery

1. The role of Rho kinase in Ca(2+) sensitization of the contractile apparatus in smooth muscle was investigated in the bovine middle cerebral artery. 2. U46619, a thromboxane A(2) analog, induced a greater sustained contraction with a smaller [Ca(2+)](i) elevation than that seen with 118 mM K(+). T...

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Hlavní autoři: Maeda, Yoshihisa, Hirano, Katsuya, Nishimura, Junji, Sasaki, Tomio, Kanaide, Hideo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574090/
https://ncbi.nlm.nih.gov/pubmed/14530221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705487
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