Vanilloid type 1 receptors (VR1) on trigeminal sensory nerve fibres play a minor role in neurogenic dural vasodilatation, and are involved in capsaicin-induced dural dilation

1. Capsaicin, the active substance in chilli peppers, activates the vanilloid type 1 receptor (VR1) rather than the vanilloid-like receptor (VRL1) in the trigeminal ganglion and nucleus of small and medium C- and Aδ-fibres. 2. Capsaicin induces calcitonin gene-related peptide (CGRP) release when VR1...

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Bibliographic Details
Main Authors: Akerman, S, Kaube, H, Goadsby, P J
Format: Artigo
Language:Inglês
Published: 2003
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574074/
https://ncbi.nlm.nih.gov/pubmed/14534154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705486
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