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Nitric oxide synthase inhibitors can antagonize neurogenic and calcitonin gene-related peptide induced dilation of dural meningeal vessels

1. The detailed pathophysiology of migraine is beginning to be understood and is likely to involve activation of trigeminovascular afferents. 2. Clinically effective anti-migraine compounds are believed to have actions that include peripheral inhibition of calcitonin gene-related peptide (CGRP) rele...

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Autori principali: Akerman, S, Williamson, D J, Kaube, H, Goadsby, P J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573468/
https://ncbi.nlm.nih.gov/pubmed/12183331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704842
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