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Roles of K(ATP) channels in delayed cardioprotection and intracellular Ca(2+) in the rat heart as revealed by κ-opioid receptor stimulation with U50,488H

1. The effect of preconditioning with U50,488 H (UP), a selective kappa-opioid receptor (κ-OR) agonist, on infarct size and intracellular Ca(2+) ([Ca(2+)](i)) in the heart subjected to ischaemic insults were studied and evaluated. U50,488 H administered intravenously reduced the infarct size 18–48 h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Mai, Zhou, Jing-Jun, Kam, Kenneth Wan-Lung, Qi, Jian-Song, Yan, Wing-Yi, Wu, Song, Wong, Tak-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574065/
https://ncbi.nlm.nih.gov/pubmed/14534156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705475
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