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Role of protein kinase C-epsilon in the development of κ-opioid receptor tolerance to U50,488H in rat ventricular myocytes
1. The role of protein kinase C-epsilon (PKC-ε) in the development of κ-opioid receptor (κ-OR) tolerance to the effects of trans-(±)-3,4-dichloro-N-methyl-N-(2-[1-pyrrolidinyl]cyclohexyl) (U50,488H), the selective agonist of κ-OR, was determined in rat ventricular myocytes. 2. Incubation of ventricu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573305/ https://ncbi.nlm.nih.gov/pubmed/11934807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704640 |
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