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CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin(22–52), CGRP(8–37) and BIBN4096BS

1. Adrenomedullin (AM) has two known receptors formed by the calcitonin receptor-like receptor (CL) and receptor activity-modifying protein (RAMP) 2 or 3: We report the effects of the antagonist fragments of human AM and CGRP (AM(22–52) and CGRP(8–37)) in inhibiting AM at human (h), rat (r) and mixe...

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Autori principali: Hay, D L, Howitt, S G, Conner, A C, Schindler, M, Smith, D M, Poyner, D R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574059/
https://ncbi.nlm.nih.gov/pubmed/12970090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705472
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