Dopaminergic mechanisms underlying bladder hyperactivity in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the nigrostriatal pathway

1. This study was undertaken to elucidate dopaminergic mechanisms underlying bladder hyperactivity in a rat model of Parkinson's disease (PD) induced by a unilateral 6-OHDA injection into the substantia nigra pars compacta. 2. In 6-OHDA-lesioned rats, voided volume per micturition (0.41±0.04 ml...

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Detalhes bibliográficos
Main Authors: Yoshimura, Naoki, Kuno, Sadako, Chancellor, Michael B, de Groat, William C, Seki, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573982/
https://ncbi.nlm.nih.gov/pubmed/12922929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705388
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