Human estrogen sulfotransferase (SULT1E1) pharmacogenomics: gene resequencing and functional genomics

1. Estrogens are used as drugs and estrogen exposure is a risk factor for hormone-dependent diseases such as breast cancer. Sulfate conjugation is an important pathway for estrogen metabolism. The sulfotransferase (SULT) enzyme SULT1E1 has the lowest K(m) values for estrogens and catecholestrogens o...

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Main Authors: Adjei, Araba A, Thomae, Bianca A, Prondzinski, Janel L, Eckloff, Bruce W, Wieben, Eric D, Weinshilboum, Richard M
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573968/
https://ncbi.nlm.nih.gov/pubmed/12922923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705369
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