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Malondialdehyde inhibits cardiac contractile function in ventricular myocytes via a p38 mitogen-activated protein kinase-dependent mechanism

1. Increased oxidative stress plays a significant role in the etiology of cardiovascular disease. Lipid peroxidation, initiated in the presence of hydroxy radicals resulting in the production of malondialdehyde, directly produces oxidative stress. This study was designed to examine the direct impact...

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Detalhes bibliográficos
Main Authors: Folden, David V, Gupta, Akanksha, Sharma, Avadhesh C, Li, Shi-Yan, Saari, Jack T, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573967/
https://ncbi.nlm.nih.gov/pubmed/12890710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705384
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