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Contractile Response of Norepinephrine is modulated by Caspase-3 in Adult Rat Ventricular Myocytes Isolated from Septic Rat Heart

Sepsis accounts for 50% of intensive care unit deaths due to cardiac dysfunction. The cellular mechanisms following norepinephrine (NE) during sepsis are undefined. Using a septic adult rat ventricular myocyte (ARVM) paradigm, we examined the molecular mechanism responsible for the blunted contracti...

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Detalhes bibliográficos
Main Authors: Chopra, Mani, Sharma, Avadhesh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735575/
https://ncbi.nlm.nih.gov/pubmed/19394424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2009.04.009
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