Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte–endothelial adherence in response to aspirin

1. Unlike other nonsteroidal anti-inflammatory drugs that inhibit formation of cyclooxygenase (COX)-dependent eicosanoids, acetylation of COX-2 by aspirin switches eicosanoid biosynthesis from prostaglandin E(2) (PGE(2)) to 15-epi-lipoxin A(4) (15-epi-LXA(4) or aspirin-triggered lipoxin, ATL). ATL f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fiorucci, Stefano, Distrutti, Eleonora, Mencarelli, Andrea, Morelli, Antonio, Laufor, Stefan A, Cirino, Giuseppe, Wallace, John L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573955/
https://ncbi.nlm.nih.gov/pubmed/12890715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705356
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg