Antidepressant fluoxetine enhances glucocorticoid receptor function in vitro by modulating membrane steroid transporters

1. Incubation of LMCAT fibroblast cells with antidepressants potentiates glucocorticoid receptor (GR)-mediated gene transcription in the presence of dexamethasone and cortisol, but not of corticosterone. We have shown that antidepressants do so by inhibiting the LMCAT cell membrane steroid transport...

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Main Authors: Pariante, Carmine M, Kim, Richard B, Makoff, Andrew, Kerwin, Robert W
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573949/
https://ncbi.nlm.nih.gov/pubmed/12871829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705357
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