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Antidepressant fluoxetine enhances glucocorticoid receptor function in vitro by modulating membrane steroid transporters

1. Incubation of LMCAT fibroblast cells with antidepressants potentiates glucocorticoid receptor (GR)-mediated gene transcription in the presence of dexamethasone and cortisol, but not of corticosterone. We have shown that antidepressants do so by inhibiting the LMCAT cell membrane steroid transport...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pariante, Carmine M, Kim, Richard B, Makoff, Andrew, Kerwin, Robert W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573949/
https://ncbi.nlm.nih.gov/pubmed/12871829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705357
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