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The critical role of leukotriene B(4) in antigen-induced mechanical hyperalgesia in immunised rats
1. We investigated the mediators responsible for mechanical hypersensitivity induced by antigen challenge in rats immunised with ovalbumin (OVA). 2. Challenge with OVA (12.5–100 μg, intraplantar) caused a dose- and time-dependent mechanical hypersensitivity, which peaked 3 h after, decreased thereaf...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573940/ https://ncbi.nlm.nih.gov/pubmed/12871832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705346 |
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