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Reactive oxygen species induce swelling and cytochrome c release but not transmembrane depolarization in isolated rat brain mitochondria

1. In this study, we have used isolated brain mitochondria to investigate the effects of superoxide anions (O(2)(−)) on mitochondrial parameters related to apoptosis, such as swelling, potential, enzymatic activity, NAD(P)H, cytochrome c release, and caspase activity. 2. Addition of the reactive oxy...

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Detalhes bibliográficos
Main Authors: Galindo, María F, Jordán, Joaquín, González-García, Carmen, Ceña, Valentín
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573905/
https://ncbi.nlm.nih.gov/pubmed/12813003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705309
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